Cisplatin lagerung

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August undefined, 2024

WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in … WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), intravenous solution (1 mg/mL) Drug class: Alkylating agents Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. Uses Warnings Before taking …

HIGHLIGHTS OF PRESCRIBING INFORMATION - Food and …

WebMaterial Name: Cisplatin Solution for Injection - 0.5 and 1 mg/ml Trade Name: Platamine; Cisplatino; Cisplatine; Platiblastin; Plastisil; Platiblastin S Chemical Family: Mixture … WebApr 6, 2024 · Cisplatin (Platinol) is an inorganic coordination complex with a broad range of antitumor activity. It is especially useful in the treatment of testicular and ovarian cancer. It binds to DNA at nucleophilic sites, such as the N7 and O6 of guanine, producing alterations in DNA structure and inhibition of DNA synthesis. ready 2 bounce

CISplatin: Dosage, Mechanism/Onset of Action, Half …

WebDie Heilwirkung erfordert eine von der Tumorart und Fraktionierung abhängige Gesamtdosis von 20 bis 80 Gray, die in Abhängigkeit vom Behandlungsschema in einer Sitzung oder über mehrere Wochen verteilt verabreicht wird. WebApr 5, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. Advanced … WebPRODUCT INFORMATION – DBL™ CISPLATIN INJECTION(CISPLATIN) 1. NAME OF THE MEDICINE Cisplatin 2. QUALITATIVE AND QUANTITATIVE COMPOSITION … how to take a break from therapy

Frontiers The Molecular Basis and Therapeutic Aspects of Cisplatin ...

Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, and germ cell tumors. Because of its widespread use, the cure rate for testicular cancer has increased from 10% to 85… WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the … how to take a breath bookWebMar 24, 2016 · The encapsulated cisplatin concentration measured by HPLC was 1.2 mg/mL, which is close to the concentration of conventional cisplatin formulations. The lipid concentration (25.39 ± 4.06 mg/mL) was considered safe and did not cause any observable toxicity in animals. how to take a break from work

"WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer … " - Cisplatin lagerung

Cisplatin lagerung

Cisplatin: a review of toxicities and therapeutic applications

WebCisplatin adducts are Guanine-Guanine (GG) DNA intrastrand cross links caused by the chemical compound Cisplatin. Cisplatin is used as a chemotherapy agent that contains … WebCisplatin Injection is a sterile, isotonic, preservative free solution containing cisplatin 1mg/mL. For the full list of excipients, see Section 6.1 List of excipients. 3. …

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WebNach längerer Lagerung weist es häufig einen fauligen Geruch (nach Dimethylsulfid) auf. Mit einem Schmelzpunkt bei 18 °C kann die Substanz nur wenig unterhalb der Raumtemperatur erstarren. [9] Die Schmelzenthalpie beträgt 14,37 kJ·mol −1. [10] Bei Normaldruck siedet die Verbindung bei 189 °C. [11] WebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost all patients treated with cisplatin …

WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. WebApr 1, 2016 · By using two pairs of genetically matched cisplatin-sensitive and cisplatin-resistant ovarian cancer cell lines, we tested the hypothesis that downregulating hypoxia-inducible factor-1 (HIF-1), which regulates metabolic enzymes involved in glycolysis, is a promising strategy for overcoming cisplatin resistance of human ovarian cancer cells.

WebCisplatin is a chemotherapy drug used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, breast cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumor, and neuroblastoma. It is administered by injection into a vein. Cisplatin Uses WebApr 12, 2024 · Accord has cisplatin 1 mg/mL 50 mL and 100 mL vials on back order and the company cannot estimate a release date. Fresenius Kabi has cisplatin 1 mg/mL 50 mL, 100 mL, and 200 mL vials on back order and the company estimates a release date of mid-April 2024 for the 50 mL vials and mid- to late-April 2024 for the 100 mL and 200 mL vials.

WebCisplatin for injection has been administered at 75 mg/m. 2 . to 100 mg/m. intravenously per cycle once every 3 to 4 weeks on Day 1. Other doses and combination regimens have been used. 2.4 Advanced Bladder Cancer . Cisplatin for injection has been administered at 50 mg/m. 2 . to 70 mg/m. intravenously per cycle once every 3 to 4 weeks.

WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … how to take a break from drinkingWebCisplatin Injection infusion concentrate is a clear, colorless, sterile aqueous solution available in amber vials. Each 50 mL or 100 mL amber vial of infusion concentrate … ready 2 castWebFür die Monotherapie werden die beiden folgenden Dosierungsregime empfohlen: – Einzeldosis von 50 bis 120 mg/m² Kör- peroberfläche alle 3 bis 4 Wochen – 15 bis 20 mg/m² pro Tag über fünf Tage alle 3 bis 4 Wochen. Wird Cisplatin im Rahmen einer … how to take a break on facebookWebSep 15, 2024 · Cisplatin is a prescription medicine used to treat the symptoms of cancer in the testicles (Metastatic Testicular Tumors), bladder (Advanced Bladder Cancer) and … how to take a cat\u0027s temperatureWebFeb 17, 2024 · Cisplatin inhibits DNA synthesis by the formation of DNA cross-links; denatures the double helix; covalently binds to DNA bases and disrupts DNA function; may also bind to proteins; the cis -isomer is 14 … how to take a castleWebOct 22, 2024 · Cisplatin is an alkylating agent which induces DNA damage through the formation of cisplatin-DNA adducts, leading to cell cycle arrest and apoptosis. In the management of advanced OSCC, cisplatin-based chemotherapy or chemoradiotherapy has been considered as the first-line treatment. how to take a cat on a long car tripWebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference standard for the determination of the analyte in plasma, cancer cell, and tumor samples by high-performance liquid chromatographic assay. how to take a capture on pc