WebAlzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal … Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is approximately 30 kDa and, like all galectins, contains a carbohydrate-recognition-binding domain (CRD) of about 130 … See more Galectin-3 has an affinity for beta-galactosides and exhibits antimicrobial activity against bacteria and fungi. This protein has been shown to be involved in the following biological processes: cell adhesion, … See more Fibrosis A correlation between galectin-3 expression levels and various types of fibrosis has … See more Cardiovascular risk indicator Chronic heart failure has been found to be indicated by a galectin-3 tests, using the ARCHITECT See more LGALS3 has been shown to interact with LGALS3BP. In melanocytic cells LGALS3 gene expression may be … See more
Recombinant Human Galectin 3 protein (His tag) (ab179972)
WebJan 26, 2024 · Galectin-3 (Gal-3) regulates basic cellular functions such as cell-cell and cell-matrix interactions, growth, proliferation, differentiation, and inflammation. It is not … WebAug 16, 2024 · Disarming Galectin-3, Cancer’s Bodyguard. Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. Galectin-3 also prevents apoptosis of cancer … motorsport manager tips reddit
Galectin 3 - an overview ScienceDirect Topics
WebProduct Specific Information. MA1-940 detects galectin-3 from human, mouse and rat tissues. MA1-940 has been successfully used in Western blot, immunohistochemistry, immunofluorescence, immunocytochemistry … WebMar 28, 2024 · Introduction. Galectin-3 is a beta-galactoside-binding mammalian lectin with a C‐terminal carbohydrate recognition domain (CRD) linked to a proline, glycine, and tyrosine rich additional N‐terminal domain [1], [2], [3].The CRD of galectin-3 can bind several cell surface glycoproteins and oligomerization mediated by the N-terminal … WebDec 10, 2024 · 12/10/2024. First described in 1971, the galectin-3 protein has emerged over the last decade as a major focus of research and pharmaceutical development for a wide range of different diseases. A brief survey of the articles searchable on PubMed and the companies involved in the development of galectin-3 inhibitors show the broad … motorsport manager steam won\u0027t start