Ion-682884
Web15 apr. 2024 · This study aims to determine whether subcutaneous injection of an antisense oligonucleotide drug, known as ION-682884, that has been specifically designed to … WebEplontersen (ION-682884), a ligand-conjugated antisense oligonucleotide designed to degrade hepatic TTR mRNA, is being evaluated for the treatment of ATTRv amyloidosis with polyneuropathy...
Ion-682884
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Web15 apr. 2024 · Because ION-682884 is an antisense oligonucleotide similar to inotersen and because inotersen has been associated with thrombocytopenia and worsening renal … WebSatisfactory completion of Treatment Period and the End of Treatment Visit of the Index Study (ION-682884-CS2) OR diagnosis of ATTR-CM and satisfactory participation on …
Web17 apr. 2024 · This study aims to determine whether subcutaneous injection of an antisense oligonucleotide drug, known as ION-682884, that has been specifically designed to … Web13 nov. 2024 · ION-682884-CS2 (EudraCT No: 2024-002835-27) is a Phase 3 global, double-blind, randomized, placebo-controlled study assessing the efficacy and safety of …
Web13 nov. 2024 · ION-682884-CS2 (EudraCT No: 2024-002835-27) is a Phase 3 global, double-blind, randomized, placebo-controlled study assessing the efficacy and safety of … WebAims: Amyloidogenic transthyretin (ATTR) amyloidosis is a fatal disease characterized by progressive cardiomyopathy and/or polyneuropathy. AKCEA-TTR-L Rx (ION-682884) is a ligand-conjugated antisense drug designed for receptor-mediated uptake by hepatocytes, the primary source of circulating transthyretin (TTR). Enhanced delivery of the antisense …
WebION-682884. Volwassenen met met familiale transthyretine-gemedieerde amyloïde polyneuropathie. NL74259.000.20. RO7248824. Gezonde volwassen mannen. NL75028.000.21. ION373. Kinderen van 2 jaar en ouder, adolescenten en volwassenen met de ziekte van Alexander. NL75086.000.20. AKCEA-APOCIII-LRX (ISIS678354), …
WebION-682884-CS13 ION-682884 (eplonterseno) PHARMACEUTICAL RESEARCH ASSOCIATES LTDA EudraCT: 2024-001427-40 AG348-C-020 AG-348(Mitapivate) PPD DO BRASIL SUPORTE A PESQUISA CLINICA LTDA NCT05031780 Foram liberados por decurso de prazo 4 ensaios clínicos, conforme previsto no Art.36 da RDC 09/2015. … grand i10 hatchback 2019WebDesign and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-L Rx (ION-682884-CS3) in Hereditary Transthyretin … chinese food buena vistaWebEplontersen, formerly known as AKCEA-TTR-LRx and ION-682884, is an RNA-targeted therapy being co-developed by Ionis Pharmaceuticals and AstraZeneca for all forms of … grand i10 magna on road priceWebThe European Union Clinical Trials Register allows you to search for protocol and results information on: interventional clinical trials that are conducted in the European Union (EU) and the European Economic Area (EEA); clinical trials conducted outside the EU / EEA that are linked to European paediatric-medicine development. chinese food budd lakeWebIONIS (ION-682884-CS2) INCLUSION Criteria Must have given written informed consent (signed and dated) and any authorizations required by local law and be able to comply … chinese food buellton caWeb13 nov. 2024 · ION-682884-CS2 (EudraCT No: 2024-002835-27) is a Phase 3 global, double-blind, randomized, placebo-controlled study assessing the efficacy and safety of AKCEA-TTR-LRx (ION-682884) in hATTR-CM or ... grand i10 hatchback gl mid taWebThe Ionis antisense pipeline Our antisense technology platform has served as a springboard for drug discovery and realized hope for patients with unmet needs. Our broad, diverse pipeline has more than 40 potential … grand i10 hatchback 2022 precio