Ip 10 chemokine
Web1 jul. 1995 · Furthermore, IP-10 shares with PF4 the ability to inhibit endothelial cell proliferation (IC50 = 150 nM). These studies demonstrate specificity in the interaction of … Web7 nov. 2024 · IP-10 was originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. The mouse homolog of human IP-10, CRG-2, shares …
Ip 10 chemokine
Did you know?
Web28 apr. 2024 · IP-10 (CXCL10) is regarded as a “key driver chemokine” attracting CD8+ and CD4+ T cells to tumor sites and potentiating their function . In addition, IP-10 is a major chemokine recruiting natural killer … Web1 aug. 1997 · Another non-ELR CXC chemokine with antiangiogenic properties is IP-10, the product of an interferon-γ (IFN-γ)-inducible gene cloned from U937 cells. 42 A variety of cell types express IP-10 in vitro including mononuclear cells, keratinocytes, fibroblasts, endothelial cells, and T lymphocytes. 42 In the mouse, IFN-γ administration induces high …
Web1 jun. 2004 · Human interferon-inducible protein 10 (IP-10; HGMW-approved gene symbol CXCL10) is an ELR − CXC chemokine that contains binding domains for both the chemokine receptor CXCR3 and glycosaminoglycans. IP-10 has been recently demonstrated to be a potent angiostatic protein in vivo. Web(3) Interferon-gamma-induced protein 10 (IP-10) IP-10 is another chemokine with effects similar to those of IL-8. Unlike MGSA, IP-10 is inducible by interferon-7 or TNF-a (Boorsma etal, 1993). IP-10 is also expressed in vivo after application of contact sensitizer or irritants (Kaplan et al, 1987) and may contribute to skin inflam-
WebSuppression of IP-10 synthesis during the healing phase may allow formation of the wound neovessels, a critical process for infarct healing. Chemokine expression is also noted after a single brief ischemic insult in the absence of myocardial infarction, suggesting a potential role for a chemokine-induced inflammatory response in noninfarctive ischemic … Web1 aug. 2001 · Chemokines were used at the concentrations indicated. Supernatants from high-density cultures of leukemia cells were collected after 3 days of culture at 37°C, 5% CO 2, in AIM V medium. All supernatants were filtered and frozen. Reverse transcription–polymerase chain reaction
Web18 feb. 2024 · Upon activation, T cells and NK cells upregulate expression of the chemokine receptor, C–X–C chemokine receptor (CXCR) 3. CXCR3-expressing cells …
Webabstract = "IP-10, a member of the CXC family of chemokines, is considered to play an important role in inflammation via its T-cell chemotactic and adhesion-promoting … the pink house cumbriaWeb1 mrt. 2001 · Here, we focused on interferon-inducible protein-10 (IP-10), a chemokine that promotes the migration of activated T-helper 1 (Th1) cells and measured serum IP-10 levels in patients with human type 1 diabetes, which is regarded as a Th1-mediated disease. the pink house jackson msWebCXCL9, CXCL10, and CXCL11 (also known as Mig, IP-10, and I-TAC, respectively) form a structurally and functionally related subgroup of non-ELR CXC chemokines that … side effect of rifampinWeb23 jun. 2024 · IFN-γ-inducible protein 10 (IP-10, CXCL10) is a 10 kDa chemokine secreted from cells stimulated with type I and II interferons (IFNs) and lipopolysaccharide … the pink house lulworthWeb11 jun. 2024 · C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the … the pink house isle of wightWebIP-10 is a CXC chemokine that is induced from most cells in response to both type I and type II interferon stimulation and LPS. IP-10 is chemotactic for activated T cells and NK … side effect of robitussinWeb1 apr. 2002 · We initially identified human IFN-γ-inducible protein of 10 kDa (IP-10/CXCL10) 5 as an early response gene induced by IFN-γ in U937 cells (a monocyte-like cell line) … side effect of rowatinex